Prof. Hill Gaston read medicine at Lincoln College, Oxford and undertook general medical training in London and Bristol. Research training began in Bristol as a Cancer Research Campaign Fellow, and postdoctoral training at Stanford with a Medical Research Council travelling fellowship. He returned to the UK to the Department of Rheumatology in Birmingham where he was Wellcome Trust Senior Clinical Fellow and honorary consultant, before moving to Cambridge as the foundation Professor of Rheumatology. He is director of studies in Clinical Medicine at St. Edmund’s College, and takes an active role in research and education in rheumatology and immunology through the British Society for Rheumatology and the Arthritis Research Campaign

His research interests are in immunological mechanisms in rheumatic disease, and interactions between infection and the immune system. Prof. Gaston has an active research team of postdoctoral researchers and graduate students, working in cellular immunology, particularly T cell cloning (see Prof Gaston is married to a local G.P. and has two children; leisure interests include music (listening, not making), reading (biographies), and travel. He is an active member and past churchwarden of a local Anglican church, Holy Trinity, Cambridge.

Recent Publications

  • Jarvis, L.B., Matyzak, M.K., Duggleby, R.D., Goodall, J.C., Hall, F. C., and Gaston, J.S.H. Autoreactive human peripheral blood CD8+ T cells with a regulatory phenotype and function. Eur. J. Immunol. 35:2896-2908 (2005).
  • Goodall, J.C., Ellis, L. and Gaston, J.S.H.. Spondyloarthritis-associated and non-spondyloarthritis associated B27 subtypes differ in their dependence upon tapasin for surface expression and their incorporation into the peptide loading complex. Arthritis and Rheumatism. In press. (2005)
  • Matyszak, M.K. and Gaston, J.S.H. Chlamydia trachomatis-specific human CD8+ T cells show two patterns of antigen recognition. Infect. Immun. 72(8): 4357-67 (2004).
  • Lillicrap, M.S., Duggleby, R.C., Gaston, J.S.H. and Goodall. J.C. T cell recognition of a highly conserved epitope in heat shock protein 60: self tolerance maintained by distinguishing between asparagine and aspartic acid. International Immunology 16:405-414 (2004).
  • Cox, C.J., Kempsell, K.E. and Gaston, J.S.H. Investigation of infectious agents associated with arthritis by RT-PCR of bacterial rRNA. Arthritis Research and Therapy 5:R1-8.(2003).
  • Gaston, J.S.H. Reactive arthritis and enteropathic arthropathy. Chapter in Oxford Textbook of Rheumatology, 3rd edition, eds. D.A. Isenberg, P. Maddison, P. Woo, D. Glass, and F. Breedveld. Oxford University Press , Pp779-786 (2004).
  • Gaston, J.S.H. Reactive arthritis. Chapter in Oxford textbook of Medicine, 4th edition, eds. D.A. Warrell. T.M. Cox, Firth, J.D. and Benz, Jr, E.J, Oxford University Press. vol. 3 pp 57-61 (2004).
  • Gaston, J.S.H. Cellular Immunity in Rheumatoid Arthritis. Chapter in Rheumatology, 3rd edition, eds. M.C. Hochberg, A.J. Silman, J.S. Smolen, M.E. Weinblatt, M.H. Weisman, Mosby-Harcourt. Pp 843-850 (2003).

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