Dr Simon Kolstoe is a senior fellow in the School of Biological Sciences, University of Portsmouth. Dr Kolstoe has a Ph.D. in Biochemistry and a first class B.Sc. Hons. in Biomedical Sciences, both from the University of Southampton.
Alongside biomedical research, Dr Kolstoe is currently studying for a cross-disciplined degree from the Open University, helps coordinate the South Central branch of Christians in Science, and speaks and writes on science and faith issues in his local community.
Selected Science Publications
- M. B. Pepys, J. Herbert, W. L. Hutchinson, G. A. Tennent, H. J. Lachmann, J. R. Gallimore, L. B. Lovat, T. Bartfai, A. Alanine, C. Hertel, T. Hoffmann, R. Jakob-Roetne, R. D. Norcross, J. A. Kemp, K. Yamamura, M. Suzuki, G. W. Taylork, S. Murray, D.Thompson, A. Purvis, S. Kolstoe, S. P. Wood and P. N. Hawkins. (2002) Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature 417:254-259.
- S. Kolstoe and S. Wood (2004) Perspectives for Drug Intervention in Amyloid Disease. Current Drug Targets 5(2):151-158.
- Mark B. Pepys, Gideon M. Hirschfield, Glenys A. Tennent, Ruth J. Gallimore, Melvyn, C. Kahan, Vittorio Bellotti, Philip N. Hawkins, Rebecca M. Myers, Martin D. Smith, Alessandra Polara, Alexander Cobb, Steven V. Ley, Andrew Aquilina, Carol Robinson, Isam Sharif, Gillian A. Gray, Caroline A. Sabin, Michelle C. Jenvey, Simon E. Kolstoe, Darren Thompson and Stephen P. Wood. (2006) Targeting C-reactive protein for treatment of cardiovascular disease Nature 440:1217-1221.
- Raj Gill, Simon E. Kolstoe, Fiyaz Mohammed, Abeer Al D-Dass, Jonathan B. Coper, Stephen P. Wood and Peter M. Shoolingin-Jordon (2009) The structure of human porphobilinogen deaminase at 2.8A: the molecular basis of acute intermittent porphyria. Biochemical Journal 420(1):17-25.
- Simon E. Kolstoe, Basil H. Ridha, Vittorio Bellotti, Nan Wang, Carol V. Robinson, Sebastian J. Crutch, Geoffrey Keir, Riitta Kukkastenvehmas, J. Ruth Gallimore, Winston L. Hutchinson, Philip N. Hawkins, Stephen P. Wood, Martin N. Rossor, and Mark B. Pepys (2009) Molecular dissection of Alzheimer’s disease neuropathology by depletion of serum amyloid P component. PNAS 106(18):7619-23.